Mechanism of Action
Femalefil (Tadalafil) is a phosphodiesterase enzyme (PDE5) inhibitor. This enzyme is responsible for the degradationcyclic guanosine monophosphate (Cgmp) Produced in reaction to sexual stimulation. The more Cgmpis available Femalefil (Tadalafil) inhibits the PDE5 enzyme, preserving Cgmp levels, therefore aiding sexual viability and durability Filling occurs because the blood vessels that bring blood to the vagina and deliver more blood to vagina, and, at the same time, the blood vessels that take blood away from the vagina remove less blood from the vagina. Sexual stimulation that leads to a vaginal flush causes the production and release of nitric oxide in the vagina.
It is the cGMP that is primarily responsible for increasing and decreasing the size of the blood vessels carrying blood to and from the vagina, respectively, and causing the flush. When the cGMP is destroyed by another enzyme, phosphodiesterase-5, the blood vessels return to their normal size, blood leaves the vaginal area, and the flush ends. Femalefil (Tadalafil) prevents phosphodiesterase-5 from destroying cGMP so that cGMP stays around longer. The persistence of CGMP leads to a more prolonged engorgement of the vaginal flush with blood. It relaxes muscles and increases blood flow to particular areas of the body.